DOTA-PEG3-SCO
DOTA-PEG3-SCO can be used in radiopharmacy, targeted cancer therapy, and bioorthogonal chemistry, particularly in areas such as diagnostic imaging and personalized medicine.
SCOserves as a click chemistry handle that readily reacts with tetrazine groupss and azides on a target molecule. DOTA can chelate divalent and trivalent cations, e.g. Gallium
Catalogue | SC-3002 |
---|---|
Formula | C33H56N6O12 |
CAS | -- |
MW | 728,84 |
Appearance | white powder |
Purity | >97% (HPLC-UV λ=254nm) |
Solubility | Soluble in water |
Size | 10mg / 50mg |
Storage | Keep cool and dry. Protect from light and moisture. Store at - 20°C on arrival. |
Possible applications DOTA-PEG3-SCO:
-
Radiopharmacy (Diagnostic Imaging): This substance could be used for PET imaging, where the DOTA molecule is conjugated with a radioactive isotope (e.g., Gallium-68). This compound could then be used to locate tumors or other diseased tissues in the body.
-
Targeted Cancer Therapy: By utilizing BCN and bioorthogonal chemistry, DOTA-PEG3-SCO could be employed in the development of targeted therapies. The substance could specifically bind to cancer cells and deliver a therapeutic agent (e.g., a radioactive isotope or a cytostatic drug) directly to them.
-
Bioorthogonal Chemistry: This compound could be used in the research and development of bioorthogonal markers and therapeutic systems, where DOTA-PEG3-SCO reacts specifically with other bioorthogonal systems (e.g., tetrazine) to deliver markers or therapeutic molecules to specific target structures.