Click Amino Acid / trans-Cyclooct-2-en – L - Lysine (TCO*A)

trans-Cyclooct-2-en – L - Lysine for copper-free Click-Chemistry (A: axial isomer) For in vivo bioorthogonal chemical reactions, strain-promoted inverse electron-demand Diels-Alder cycloaddition (SPIEDAC), can be used to efficiently and rapidly attach fluorophores conjugated to all kinds of Tetrazines !
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Catalogue SC-8008
Formula C15H26N2O4
CAS 1801936-26-4
MW 298.38
Appearance White powder
Purity min. 95 % (HPLC)
Solubility Stock solution: 100mM in 0.2M NaOH, 15% DMSO - Freshly before adding to cells: 1:4 dilution in 1M HEPES. Use this dilution immediately, and do not store!
Size 500 mg / 1 g
Storage Keep cool and dry.
Artificial Amino Acid for copper-free Click Chemistry - works well with Azides and all kind of Tetrazines ! [T. Plass et al., Angew. Chem., Int. Ed. Engl. 2011, 50, 3878–3881 // T. Plass et al., Angew. Chem., Int. Ed. Engl. 2012, 51, 4166–4170 // I. Nikic, Angew. Chem., Int. Ed. Engl. 2014, 53, 1]