caged-Ins(145)P3O6
DMNB-caged IP3 is a photolabile derivative of D-myo-inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) for efficient photoactivation with UV light (Sodium Salt)
| Katalognummer | cag-6-145 |
|---|---|
| Formel | C15H18NO19P3Na6 |
| CAS | 887903-55-1 (H+) |
| MW | 747.16 |
| Aussehen | Lyophilized off-white powder |
| Reinheit | > 90% |
| Löslichkeit | in water |
| Größe | 100 µg |
| Aufbewahrung | Keep cool and dry. Protect from light and moisture |
DMNB-caged IP3 (caged Ins(1,4,5)P3) is a photolabile derivative of D-myo-inositol 1,4,5-trisphosphate (IP3). The DMNB (2-nitro-4,5-dimethoxybenzyl) protecting group enables efficient photochemical release of active Ins(1,4,5)P3 upon irradiation with UV light.
This caged inositol phosphate is photolyzed with UV light approximately three times more efficiently than the widely used NPE-caged D-myo-inositol 1,4,5-trisphosphate derivative, making it particularly suitable for rapid and controlled photoactivation of IP3-dependent signaling.
References:
Kantevari S. et al., ChemBioChem 2006, 7, 174–180. DOI: 10.1002/cbic.200500345
Cheng H. et al., Cells 2024, 13, 1455. DOI: 10.3390/cells13171455
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caged-Ins(145)P3 / PM750,00 € -
caged-Ins(145)P3 / PM650,00 € -
caged-Ins(145)P3 P4650,00 €