Here you will find TCO* and TCO reagents for bioorthogonal click chemistry. Trans-cyclooctenes react rapidly with tetrazines by strain-promoted inverse-electron-demand Diels–Alder cycloaddition (SPIEDAC) and are widely used for bioorthogonal labeling and bioconjugation. Reagents are available for the functionalization of molecules containing COOH, NH2 or SH groups, with PEG linkers of different lengths or without a linker.
