LaRee 5

FRET-reporter to measure extracellular activity of MMP12 (macrophage elastase) not linked to the plasma membrane

In stock

Catalogue

SC-0043

€500.00

Größe / Size

5 mg + €1,000.00

1 mg

Qty

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Technical Information

More Information
Catalogue	SC-0043
Formula	C71H95N11O23
CAS	NA
MW	1470.60
Appearance	Yellow powder
Purity	> 97 % (HPLC-UV
Solubility	Soluble in acetonitrile / water
Size	1 mg / 5 mg
Storage	Keep cool and dry. Protect from light and moisture.

Product Description

Soluble FRET reporter to measure extracellular activity of MMP12 (macrophage elastase) not linked to the plasma membrane. The involvement of MMP12 in several diseases, e.g. emphysema, aortic lesions, cancer, and rheumatoid arthritis, makes it an important drug target. Determination of peptide concentration: 442 nm in ethanol (ε = 44138 cm^-1 M^-1 )⁵ Fluorescence measurements in vitro: λ exc = 350 nm // λ em = 370-530 nm (Amanda Cobos-Correa et al.: Nature Chem. Biol. 2009, 5, 9: 628)