LaRee 5
FRET-reporter to measure extracellular activity of MMP12 (macrophage elastase) not linked to the plasma membrane
Auf Lager
Katalognummer
SC-0043
500,00 €
| Katalognummer | SC-0043 |
|---|---|
| Formel | C71H95N11O23 |
| CAS | NA |
| MW | 1470.60 |
| Aussehen | Yellow powder |
| Reinheit | > 97 % (HPLC-UV |
| Löslichkeit | Soluble in acetonitrile / water |
| Größe | 1 mg / 5 mg |
| Aufbewahrung | Keep cool and dry. Protect from light and moisture. |
Soluble FRET reporter to measure extracellular activity of MMP12 (macrophage elastase) not linked to the plasma membrane. The involvement of MMP12 in several diseases, e.g. emphysema, aortic lesions, cancer, and rheumatoid arthritis, makes it an important drug target. Determination of peptide concentration: 442 nm in ethanol (ε = 44138 cm-1 M-1 )5 Fluorescence measurements in vitro: λ exc = 350 nm // λ em = 370-530 nm (Amanda Cobos-Correa et al.: Nature Chem. Biol. 2009, 5, 9: 628)