SH-5
| Catalogue | SC-0044 |
|---|---|
| Formula | C29H59O10P |
| CAS | 701976-54-7 |
| MW | 598.75 |
| Appearance | Off-white solid |
| Purity | > 98% (HPLC-RI) |
| Solubility | soluble in DMSO, water |
| Size | 1 mg / 5 mg |
| Storage | Keep cool and dry. Protect from light and moisture. Store at -20°C on arrival. |
The phosphatidylinositol 3-kinase/AKT pathway is activated frequently in human cancer, and it has been implicated in tumour cell proliferation, survival, and chemoresistance.
Analogs of phosphatidyl inositol phosphates (PIAs) SH-5 and SH-6 were designed as new small drugs for preferential inhibition of Akt and killing of Akt dependent cancer cells.
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