Akt inhibitor
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Catalogue SC-0045
Formula C28H57O9P
CAS 701976-55-8
MW 568.73
Appearance Off-white solid
Purity > 98% (HPLC-RI)
Solubility soluble in DMSO, water
Size 1 mg / 5 mg
Storage Keep cool and dry. Protect from light and moisture. Store at -20°C on arrival.
The phosphatidylinositol 3-kinase/AKT pathway is activated frequently in human cancer, and it has been implicated in tumor cell proliferation, survival, and chemoresistance. Analogs of phosphatidyl inositol phosphates (PIAs) such as SH-6 were designed as new small drugs for preferential inhibition of Akt and killing of Akt dependent cancer cells.
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