Ins(1345)P4*8Na

myo-Inositol 1,3,4,5-tetrakisphosphate (Ins(1,3,4,5)P4, InsP4), octasodium salt.

Auf Lager
Katalognummer
4-0-1345-Na
Größe: 1 mg
450,00 €
Weitere Informationen
Katalognummer 4-0-1345-Na
Formel C6H8Na8O18P4
CAS 135269-51-1 (H+: 99610-76-1)
MW 675.8
Aussehen Lyophilized white powder
Reinheit > 98%
Löslichkeit in water
Größe 1 mg
Aufbewahrung Keep cool and dry. Protect from light and moisture

myo-Inositol 1,3,4,5-tetrakisphosphate (Ins(1,3,4,5)P4) is a naturally occurring inositol tetrakisphosphate formed by phosphorylation of Ins(1,4,5)P3 at the 3-position by inositol 1,4,5-trisphosphate 3-kinases.

Ins(1,3,4,5)P4 is an intermediate in cellular inositol phosphate metabolism and has been extensively investigated in the regulation of intracellular Ca2+ signaling and Ca2+ entry. It has also been shown to interact with Ins(1,4,5)P3-sensitive signaling mechanisms in several experimental systems. This product is supplied as the octasodium salt.

 

References:

Authi K.S. et al., Research and Practice in Thrombosis and Haemostasis 2024, 8, 102326. DOI: 10.1016/j.rpth.2024.102326

Lietzke S.E. et al., Molecular Cell 2000, 6, 385–394. DOI: 10.1016/S1097-2765(00)00038-1

Lückhoff A., Clapham D.E., Nature 1992, 355, 356–358. DOI: 10.1038/355356a0

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